Luis Pereira de Almeida
Luis Pereira de Almeida
University of Coimbra, CNC - Center for Neuroscience and Cell Biology & Faculty of Pharmacy & CIBB
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
N Deglon, JL Tseng, JC Bensadoun, AD Zurn, Y Arsenijevic, ...
Human gene therapy 11 (1), 179-190, 2000
miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production
AL Cardoso, JR Guedes, L Pereira de Almeida, MC Pedroso de Lima
Immunology 135 (1), 73-88, 2012
Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases
D Rufino-Ramos, PR Albuquerque, V Carmona, R Perfeito, RJ Nobre, ...
Journal of Controlled Release 262, 247-258, 2017
Lentiviral-Mediated Delivery of Mutant Huntingtin in the Striatum of Rats Induces a Selective Neuropathology Modulated by Polyglutamine Repeat Size, Huntingtin Expression Levels
L Pereira de Almeida, CA Ross, D Zala, P Aebischer, N Deglon
The Journal of Neuroscience 22 (9), 3473-3483, 2002
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease
I Nascimento-Ferreira, T Santos-Ferreira, L Sousa-Ferreira, G Auregan, ...
Brain 134 (5), 1400-1415, 2011
Gene therapy for the CNS using AAVs: the impact of systemic delivery by AAV9
J Saraiva, RJ Nobre, LP de Almeida
Journal of Controlled Release 241, 94-109, 2016
Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease
LP de Almeida, D Zala, P Aebischer, N Deglon
Neurobiology of disease 8 (3), 433-446, 2001
Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease
S Alves, I Nascimento-Ferreira, G Auregan, R Hassig, N Dufour, ...
PloS one 3 (10), e3341, 2008
MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
PM Costa, AL Cardoso, C Custódia, P Cunha, LP de Almeida, ...
Journal of Controlled Release 207, 31-39, 2015
Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model
JR Guedes, CM Custodia, RJ Silva, LP de Almeida, MC Pedroso de Lima, ...
Human molecular genetics 23 (23), 6286-6301, 2014
Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease
AT Simoes, N Gonçalves, A Koeppen, N Deglon, S Kügler, CB Duarte, ...
Brain 135 (8), 2428-2439, 2012
Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice
C Nóbrega, I Nascimento-Ferreira, I Onofre, D Albuquerque, H Hirai, ...
PloS one 8 (1), e52396, 2013
Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's …
E Regulier, L Pereira de Almeida, B Sommer, P Aebischer, N Deglon
Human gene therapy 13 (16), 1981-1990, 2002
Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?
S Alves, I Nascimento-Ferreira, N Dufour, R Hassig, G Auregan, ...
Human molecular genetics 19 (12), 2380-2394, 2010
siRNA delivery by a transferrin‐associated lipid‐based vector: a non‐viral strategy to mediate gene silencing
ALC Cardoso, S Simoes, LP De Almeida, J Pelisek, C Culmsee, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007
Role of hypothalamic neurogenesis in feeding regulation
L Sousa-Ferreira, LP de Almeida, C Cavadas
Trends in Endocrinology & Metabolism 25 (2), 80-88, 2014
Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment
PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ...
Molecular Therapy-Nucleic Acids 2, e100, 2013
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease
S Alves, E Régulier, I Nascimento-Ferreira, R Hassig, N Dufour, ...
Human molecular genetics 17 (14), 2071-2083, 2008
Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases
J Duarte-Neves, LP de Almeida, C Cavadas
Neurobiology of disease 95, 210-224, 2016
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