| Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites WR Wikoff, AT Anfora, J Liu, PG Schultz, SA Lesley, EC Peters, G Siuzdak Proceedings of the national academy of sciences 106 (10), 3698-3703, 2009 | 2786 | 2009 |
| Topologically linked protein rings in the bacteriophage HK97 capsid WR Wikoff, L Liljas, RL Duda, H Tsuruta, RW Hendrix, JE Johnson Science 289 (5487), 2129-2133, 2000 | 769 | 2000 |
| Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype LN Segal, JC Clemente, JCJ Tsay, SB Koralov, BC Keller, BG Wu, Y Li, ... Nature microbiology 1 (5), 1-11, 2016 | 507 | 2016 |
| Multiple organic anion transporters contribute to net renal excretion of uric acid SA Eraly, V Vallon, T Rieg, JA Gangoiti, WR Wikoff, G Siuzdak, ... Physiological genomics 33 (2), 180-192, 2008 | 265 | 2008 |
| Virus maturation involving large subunit rotations and local refolding JF Conway, WR Wikoff, N Cheng, RL Duda, RW Hendrix, JE Johnson, ... Science 292 (5517), 744-748, 2001 | 220 | 2001 |
| Metabolomics identifies perturbations in human disorders of propionate metabolism WR Wikoff, JA Gangoiti, BA Barshop, G SIuzDAK Clinical chemistry 53 (12), 2169-2176, 2007 | 198 | 2007 |
| The refined structure of a protein catenane: the HK97 bacteriophage capsid at 3.44 Å resolution C Helgstrand, WR Wikoff, RL Duda, RW Hendrix, JE Johnson, L Liljas Journal of molecular biology 334 (5), 885-899, 2003 | 189 | 2003 |
| Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1) WR Wikoff, MA Nagle, VL Kouznetsova, IF Tsigelny, SK Nigam Journal of proteome research 10 (6), 2842-2851, 2011 | 187 | 2011 |
| Maturation dynamics of a viral capsid: visualization of transitional intermediate states R Lata, JF Conway, N Cheng, RL Duda, RW Hendrix, WR Wikoff, ... Cell 100 (2), 253-263, 2000 | 184 | 2000 |
| Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung LN Segal, JC Clemente, BG Wu, WR Wikoff, Z Gao, Y Li, JP Ko, WN Rom, ... Thorax 72 (1), 13-22, 2017 | 165 | 2017 |
| Substrate properties of C1 inhibitor Ma (alanine 434----glutamic acid). Genetic and structural evidence suggesting that the P12-region contains critical determinants of serine … K Skriver, WR Wikoff, PA Patston, F Tausk, M Schapira, AP Kaplan, ... Journal of Biological Chemistry 266 (14), 9216, 1991 | 164 | 1991 |
| Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques WR Wikoff, G Pendyala, G Siuzdak, HS Fox The Journal of clinical investigation 118 (7), 2661-2669, 2008 | 163 | 2008 |
| Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data B Crews, WR Wikoff, GJ Patti, HK Woo, E Kalisiak, J Heideker, G Siuzdak Analytical chemistry 81 (20), 8538-8544, 2009 | 149 | 2009 |
| The structure of a neutralized virus: canine parvovirus complexed with neutralizing antibody fragment WR Wikoff, G Wang, CR Parrish, RH Cheng, ML Strassheim, TS Baker, ... Structure 2 (7), 595-607, 1994 | 120 | 1994 |
| Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment M Trupp, H Zhu, WR Wikoff, RA Baillie, ZB Zeng, PD Karp, O Fiehn, ... PloS one 7 (7), e38386, 2012 | 119 | 2012 |
| Structure determination of minute virus of mice AL Llamas-Saiz, M Agbandje-McKenna, WR Wikoff, J Bratton, P Tattersall, ... Acta Crystallographica Section D: Biological Crystallography 53 (1), 93-102, 1997 | 114 | 1997 |
| Diacetylspermine is a novel prediagnostic serum biomarker for non–small-cell lung cancer and has additive performance with pro-surfactant protein B WR Wikoff, S Hanash, B DeFelice, S Miyamoto, M Barnett, Y Zhao, ... Journal of clinical oncology 33 (33), 3880, 2015 | 106 | 2015 |
| Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma WR Wikoff, D Grapov, JF Fahrmann, B DeFelice, WN Rom, HI Pass, K Kim, ... Cancer prevention research 8 (5), 410-418, 2015 | 90 | 2015 |
| Systemic metabolomic changes in blood samples of lung cancer patients identified by gas chromatography time-of-flight mass spectrometry S Miyamoto, SL Taylor, DK Barupal, A Taguchi, G Wohlgemuth, ... Metabolites 5 (2), 192-210, 2015 | 89 | 2015 |
| Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo R Kaddurah-Daouk, MB Bogdanov, WR Wikoff, H Zhu, SH Boyle, ... Translational psychiatry 3 (1), e223-e223, 2013 | 89 | 2013 |
John E. JohnsonThe Scripps Research InstituteVerificeret mail på scripps.edu
