Martin Jennings

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Graham Pavitt (GD Pavitt)Faculty of Biology Medicine and Health, University of ManchesterVerified email at manchester.ac.uk
Christopher KershawHealthcare Scientist, North-West Genomic Laboratory Hub, Manchester University NHS Foundation TrustVerified email at manchester.ac.uk
Margherita GuaitaUniversity of ManchesterVerified email at ucsc.edu
Mark AsheThe University of ManchesterVerified email at manchester.ac.uk
Martin Baronuniversity of manchesterVerified email at manchester.ac.uk
Víctor FaundesInstitute of Nutrition and Food Technology, LabGEMVerified email at inta.uchile.cl
Siddharth BankaUniversity of Manchester and Manchester University Foundation NHS TrustVerified email at manchester.ac.uk
Siobhan CrillyThe University of GalwayVerified email at universityofgalway.ie
WILLIAM NEWMANProfessor of Translational Genomic Medicine, University of ManchesterVerified email at manchester.ac.uk
Jorge L GranadilloAssistant Professor of Pediatrics, Washington University School of Medicine in St. LouisVerified email at wustl.edu
Alan RosemanUniversity of ManchesterVerified email at manchester.ac.uk
Zakia LatifUniversity of the PunjabVerified email at pu.edu.pk
Chris GrantProfessor of Biochemistry, University of ManchesterVerified email at manchester.ac.uk
Carol V RobinsonProfessor of Chemistry University of OxfordVerified email at chem.ox.ac.uk
Chingakham Ranjit SinghAssistant ProfessorVerified email at ksu.edu
Katsura AsanoProfessor of Biology, Kansas State UniversityVerified email at ksu.edu
Donghui ZhouIndiana University School of MedicineVerified email at iupui.edu
Susan G CampbellSheffield Hallam UniversityVerified email at shu.ac.uk
Toshinobu FujiwaraKindai UniversityVerified email at phar.kindai.ac.jp
simon hubbardProfessor of Computational Biology, University of ManchesterVerified email at manchester.ac.uk

Martin Jennings

Business Development, Peak Proteins

Verified email at peakproteins.com

Protein Translation Structural Biology Biochemistry


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The structural basis of translational control by eIF2 phosphorylation T Adomavicius, M Guaita, Y Zhou, MD Jennings, Z Latif, AM Roseman, ... Nature communications 10 (1), 2136, 2019	149	2019
eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation MD Jennings, GD Pavitt Nature 465 (7296), 378-381, 2010	142	2010
eIF2B promotes eIF5 dissociation from eIF2• GDP to facilitate guanine nucleotide exchange for translation initiation MD Jennings, Y Zhou, SS Mohammad-Qureshi, D Bennett, GD Pavitt Genes & development 27 (24), 2696-2707, 2013	98	2013
eIF2B is a decameric guanine nucleotide exchange factor with a γ₂ε₂ tetrameric core Y Gordiyenko, C Schmidt, MD Jennings, D Matak-Vinkovic, GD Pavitt, ... Nature communications 5 (1), 3902, 2014	86	2014
Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes MD Jennings, CJ Kershaw, T Adomavicius, GD Pavitt Elife 6, e24542, 2017	67	2017
Mechanisms of translational regulation by a human eIF5-mimic protein CR Singh, R Watanabe, D Zhou, MD Jennings, A Fukao, B Lee, Y Ikeda, ... Nucleic acids research 39 (19), 8314-8328, 2011	57	2011
A new function and complexity for protein translation initiation factor eIF2B MD Jennings, GD Pavitt Cell cycle 13 (17), 2660-2665, 2014	52	2014
Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine V Faundes, MD Jennings, S Crilly, S Legraie, SE Withers, S Cuvertino, ... Nature communications 12 (1), 833, 2021	43	2021
Specificity and autoregulation of Notch binding by tandem WW domains in suppressor of Deltex MD Jennings, RT Blankley, M Baron, AP Golovanov, JM Avis Journal of biological chemistry 282 (39), 29032-29042, 2007	43	2007
Su(dx) E3 ubiquitin ligase–dependent and –independent functions of Polychaetoid, the Drosophila ZO-1 homologue A Djiane, H Shimizu, M Wilkin, S Mazleyrat, MD Jennings, J Avis, S Bray, ... Journal of cell biology 192 (1), 189-200, 2011	41	2011
eIF5 is a dual function GAP and GDI for eukaryotic translational control MD Jennings, GD Pavitt Small GTPases, 2010	41	2010
Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation SS Mohammad-Qureshi, MD Jennings, GD Pavitt Biochemical Society Transactions 36 (4), 658-664, 2008	36	2008
eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control MD Jennings, CJ Kershaw, C White, D Hoyle, JP Richardson, JL Costello, ... Nucleic acids research 44 (20), 9698-9709, 2016	32	2016
Integrated multi-omics reveals common properties underlying stress granule and P-body formation CJ Kershaw, MG Nelson, J Lui, CP Bates, MD Jennings, SJ Hubbard, ... RNA biology 18 (sup2), 655-673, 2021	18	2021
Interaction of the La-related protein Slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mRNAs MD Jennings, P Srivastava, CJ Kershaw, D Talavera, CM Grant, GD Pavitt Nucleic Acids Research 51 (11), 5755-5773, 2023	7	2023
GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity CJ Kershaw, MD Jennings, F Cortopassi, M Guaita, H Al-Ghafli, GD Pavitt Iscience 24 (12), 2021	7	2021
Overlapping regions of Caf20 mediate its interactions with the mRNA-5′ cap-binding protein eIF4E and with ribosomes EC Nwokoye, E AlNaseem, RA Crawford, LM Castelli, MD Jennings, ... Scientific Reports 11 (1), 13467, 2021	5	2021
Translation factor and RNA binding protein mRNA interactomes support broader RNA regulons for posttranscriptional control CJ Kershaw, MG Nelson, LM Castelli, MD Jennings, J Lui, D Talavera, ... Journal of Biological Chemistry 299 (10), 2023	1	2023
Quantifying the Binding of Fluorescently Labeled Guanine Nucleotides and Initiator tRNA to Eukaryotic Translation Initiation Factor 2 MD Jennings, GD Pavitt The Integrated Stress Response: Methods and Protocols, 89-99, 2022	1	2022
Analysing WW Domain Specificity in Suppressor of Deltex MD Jennings PQDT-Global, 2007		2007

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