Frederick J King
Frederick J King
Genomics Institute of the Novartis Research Foundation
Verified email at
Cited by
Cited by
Differentiation and reversal of malignant changes in colon cancer through PPARγ
P Sarraf, E Mueller, D Jones, FJ King, DJ DeAngelo, JB Partridge, ...
Nature medicine 4 (9), 1046-1052, 1998
An efficient rapid system for profiling the cellular activities of molecular libraries
JS Melnick, J Janes, S Kim, JY Chang, DG Sipes, D Gunderson, L Jarnes, ...
Proceedings of the National Academy of Sciences 103 (9), 3153-3158, 2006
Genome-scale functional profiling of the mammalian AP-1 signaling pathway
SK Chanda, S White, AP Orth, R Reisdorph, L Miraglia, RS Thomas, ...
Proceedings of the National Academy of Sciences 100 (21), 12153-12158, 2003
Dark chemical matter as a promising starting point for drug lead discovery
AM Wassermann, E Lounkine, D Hoepfner, G Le Goff, FJ King, C Studer, ...
Nature chemical biology 11 (12), 958-966, 2015
Dual ALK and CDK4/6 Inhibition Demonstrates Synergy against NeuroblastomaALK and CDK4/6 Inhibition in Neuroblastoma
AC Wood, K Krytska, HT Ryles, NR Infarinato, R Sano, TD Hansel, ...
Clinical Cancer Research 23 (11), 2856-2868, 2017
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ...
Nature 581 (7808), 316-322, 2020
Compound profiling devices, systems, and related methods
JY Chang, JK Mainquist, RC Downs, JS Caldwell, FJ King
US Patent App. 11/841,880, 2009
DEF-1, a novel Src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines
FJ King, E Hu, DF Harris, P Sarraf, BM Spiegelman, TM Roberts
Molecular and cellular biology 19 (3), 2330-2337, 1999
Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery
Y Wang, A Cornett, FJ King, Y Mao, F Nigsch, CG Paris, G McAllister, ...
Cell chemical biology 23 (7), 862-874, 2016
Learning from the data: mining of large high-throughput screening databases
SF Yan, FJ King, Y He, JS Caldwell, Y Zhou
Journal of chemical information and modeling 46 (6), 2381-2395, 2006
Seeing the light: luminescent reporter gene assays
L J Miraglia, F J King, R Damoiseaux
Combinatorial chemistry & high throughput screening 14 (8), 648-657, 2011
Large-scale annotation of small-molecule libraries using public databases
Y Zhou, B Zhou, K Chen, SF Yan, FJ King, S Jiang, EA Winzeler
Journal of chemical information and modeling 47 (4), 1386-1394, 2007
Compound profiling devices, systems, and related methods
J Chang, J Mainquist, R Downs, J Caldwell, F King
US Patent App. 11/387,459, 2006
Chemical and biological properties of frequent screening hits
J Che, FJ King, B Zhou, Y Zhou
Journal of chemical information and modeling 52 (4), 913-926, 2012
Pathway reporter assays reveal small molecule mechanisms of action
FJ King, DW Selinger, FA Mapa, J Janes, H Wu, TR Smith, QY Wang, ...
JALA: Journal of the Association for Laboratory Automation 14 (6), 374-382, 2009
Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling
B Da’adoosh, D Marcus, A Rayan, F King, J Che, A Goldblum
Scientific Reports 9 (1), 1-12, 2019
Activation and suppression of the TRAIL death-receptor pathway in chemotherapy sensitive and resistant follicular lymphoma cells
KW Wagner, F King, K Nomoto, DA Knee, G Hampton, M Nasoff, ...
Cancer Biology & Therapy 2 (5), 534-540, 2003
Molecular cloning and sequencing of the murine c-fgr gene.
FJ King, MD Cole
Oncogene 5 (3), 337-344, 1990
Multiplexed reporter gene assays: monitoring the cell viability and the compound kinetics on luciferase activity
MC Didiot, S Serafini, MJ Pfeifer, FJ King, CN Parker
Journal of biomolecular screening 16 (7), 786-793, 2011
Differential tumor cytotoxicity compounds and compositions
J Chyba, Q Devereax, G Hampton, F King
US Patent 7,125,997, 2006
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