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Jeong Hyun Lee
Jeong Hyun Lee
Senior Scientist, International AIDS Vaccine Initiative
Verified email at iavi.org
Title
Cited by
Cited by
Year
Highly conserved protective epitopes on influenza B viruses
C Dreyfus, NS Laursen, T Kwaks, D Zuijdgeest, R Khayat, DC Ekiert, ...
Science 337 (6100), 1343-1348, 2012
7862012
HIV-1 neutralizing antibodies induced by native-like envelope trimers
RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ...
Science 349 (6244), 2015
5332015
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ...
Nature 515 (7525), 138-142, 2014
5022014
Cross-neutralization of influenza A viruses mediated by a single antibody loop
DC Ekiert, AK Kashyap, J Steel, A Rubrum, G Bhabha, R Khayat, JH Lee, ...
Nature 489 (7417), 526-532, 2012
4852012
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers
E Falkowska, KM Le, A Ramos, KJ Doores, JH Lee, C Blattner, A Ramirez, ...
Immunity 40 (5), 657-668, 2014
4602014
Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer
JH Lee, G Ozorowski, AB Ward
Science 351 (6277), 1043-1048, 2016
4542016
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
L Kong, JH Lee, KJ Doores, CD Murin, JP Julien, R McBride, Y Liu, ...
Nature structural & molecular biology 20 (7), 796-803, 2013
4032013
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
JP Julien, D Sok, R Khayat, JH Lee, KJ Doores, LM Walker, A Ramos, ...
PLoS pathogens 9 (5), e1003342, 2013
4032013
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers
C Blattner, JH Lee, K Sliepen, R Derking, E Falkowska, AT de la Peņa, ...
Immunity 40 (5), 669-680, 2014
3892014
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
D Sok, MJ van Gils, M Pauthner, JP Julien, KL Saye-Francisco, J Hsueh, ...
Proceedings of the National Academy of Sciences 111 (49), 17624-17629, 2014
3662014
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
JP Julien, JH Lee, A Cupo, CD Murin, R Derking, S Hoffenberg, ...
Proceedings of the National Academy of Sciences 110 (11), 4351-4356, 2013
3052013
Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens
RK Abbott, JH Lee, S Menis, P Skog, M Rossi, T Ota, DW Kulp, D Bhullar, ...
Immunity 48 (1), 133-146. e6, 2018
2932018
Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein
AJ Behrens, S Vasiljevic, LK Pritchard, DJ Harvey, RS Andev, SA Krumm, ...
Cell reports 14 (11), 2695-2706, 2016
2642016
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike
L Scharf, JF Scheid, JH Lee, AP West Jr, C Chen, H Gao, ...
Cell reports 7 (3), 785-795, 2014
2562014
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure
JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ...
Immunity 46 (4), 690-702, 2017
2302017
Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans
F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ...
Immunity 43 (6), 1053-1063, 2015
2192015
Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans
F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ...
Immunity 43 (6), 1053-1063, 2015
2192015
Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
RP Ringe, RW Sanders, A Yasmeen, HJ Kim, JH Lee, A Cupo, J Korzun, ...
Proceedings of the National Academy of Sciences 110 (45), 18256-18261, 2013
2112013
Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem
C Havenar‐Daughton, JH Lee, S Crotty
Immunological Reviews 275 (1), 49-61, 2017
1642017
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans
D Sok, M Pauthner, B Briney, JH Lee, KL Saye-Francisco, J Hsueh, ...
Immunity 45 (1), 31-45, 2016
1422016
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