| Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma SS Neelapu, FL Locke, NL Bartlett, LJ Lekakis, DB Miklos, CA Jacobson, ... New England Journal of Medicine 377 (26), 2531-2544, 2017 | 4787 | 2017 |
| Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells D Lu, MY Choi, J Yu, JE Castro, TJ Kipps, DA Carson Proceedings of the National Academy of Sciences 108 (32), 13253-13257, 2011 | 443 | 2011 |
| Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a T Fukuda, L Chen, T Endo, L Tang, D Lu, JE Castro, GF Widhopf, ... Proceedings of the National Academy of Sciences 105 (8), 3047-3052, 2008 | 398 | 2008 |
| Fas modulation of apoptosis during negative selection of thymocytes JE Castro, JA Listman, BA Jacobson, Y Wang, PA Lopez, S Ju, PW Finn, ... Immunity 5 (6), 617-627, 1996 | 203 | 1996 |
| ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic … JE Castro, CE Prada, O Loria, A Kamal, L Chen, FJ Burrows, TJ Kipps Blood 106 (7), 2506-2512, 2005 | 164 | 2005 |
| Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia JE Castro, JD Sandoval-Sus, J Bole, L Rassenti, TJ Kipps Leukemia 22 (11), 2048-2053, 2008 | 150 | 2008 |
| Phase I trial: cirmtuzumab inhibits ROR1 signaling and stemness signatures in patients with chronic lymphocytic leukemia MY Choi, GF Widhopf, EM Ghia, RL Kidwell, MK Hasan, J Yu, LZ Rassenti, ... Cell Stem Cell 22 (6), 951-959. e3, 2018 | 147 | 2018 |
| Acute lymphoblastic leukemia, version 2.2015 JC Alvarnas, PA Brown, P Aoun, KK Ballen, SK Barta, U Borate, ... Journal of The national comprehensive cancer network 13 (10), 1240-1279, 2015 | 136 | 2015 |
| Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia JE Castro, DF James, JD Sandoval-Sus, S Jain, J Bole, L Rassenti, ... Leukemia 23 (10), 1779-1789, 2009 | 131 | 2009 |
| Clinical practice recommendations for use of allogeneic hematopoietic cell transplantation in chronic lymphocytic leukemia on behalf of the Guidelines Committee of the American … MA Kharfan-Dabaja, A Kumar, M Hamadani, S Stilgenbauer, P Ghia, ... Biology of Blood and Marrow Transplantation 22 (12), 2117-2125, 2016 | 119 | 2016 |
| KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results BD Shah, MR Bishop, OO Oluwole, AC Logan, MR Baer, WB Donnellan, ... Blood, The Journal of the American Society of Hematology 138 (1), 11-22, 2021 | 115 | 2021 |
| Chronic lymphocytic leukemia cells display p53-dependent drug-induced Puma upregulation WJM Mackus, AP Kater, A Grummels, LM Evers, B Hooijbrink, ... Leukemia 19 (3), 427-434, 2005 | 112 | 2005 |
| Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial DJ Winston, KM Mullane, OA Cornely, MJ Boeckh, JW Brown, SA Pergam, ... The Lancet 391 (10135), 2116-2127, 2018 | 99 | 2018 |
| Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B MK Kashyap, D Kumar, R Villa, JJ La Clair, C Benner, R Sasik, H Jones, ... Haematologica 100 (7), 945, 2015 | 95 | 2015 |
| Ulocuplumab (BMS-936564/MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway MK Kashyap, D Kumar, H Jones, CI Amaya-Chanaga, MY Choi, ... Oncotarget 7 (3), 2809, 2016 | 90 | 2016 |
| Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic … DF James, L Werner, JR Brown, WG Wierda, JC Barrientos, JE Castro, ... Journal of clinical oncology 32 (19), 2067, 2014 | 79 | 2014 |
| Kte-C19 (anti-CD19 CAR T cells) induces complete remissions in patients with refractory diffuse large B-cell lymphoma (DLBCL): results from the pivotal phase 2 Zuma-1 SS Neelapu, FL Locke, NL Bartlett, L Lekakis, D Miklos, CA Jacobson, ... Blood, The Journal of the American Society of Hematology 128 (22), LBA-6-LBA-6, 2016 | 76 | 2016 |
| Targeting the CXCR4 pathway: safety, tolerability and clinical activity of ulocuplumab (BMS-936564), an anti-CXCR4 antibody, in relapsed/refractory acute myeloid leukemia PS Becker, JM Foran, JK Altman, A Yacoub, JE Castro, P Sabbatini, ... Blood 124 (21), 386, 2014 | 69 | 2014 |
| CD154 induces p73 to overcome the resistance to apoptosis of chronic lymphocytic leukemia cells lacking functional p53 F Dicker, AP Kater, CE Prada, T Fukuda, JE Castro, G Sun, JY Wang, ... Blood 108 (10), 3450-3457, 2006 | 62 | 2006 |
| A phase I study of immune gene therapy for patients with CLL using a membrane-stable, humanized CD154 WG Wierda, JE Castro, R Aguillon, D Sampath, A Jalayer, J McMannis, ... Leukemia 24 (11), 1893-1900, 2010 | 58 | 2010 |
Thomas J. KippsProfessor of Medicine, UC San DiegoVerificeret mail på ucsd.edu
