A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. G Melillo, T Musso, A Sica, LS Taylor, GW Cox, L Varesio The Journal of experimental medicine 182 (6), 1683-1693, 1995 | 816 | 1995 |
Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization C Lo Sicco, D Reverberi, C Balbi, V Ulivi, E Principi, L Pascucci, ... Stem cells translational medicine 6 (3), 1018-1028, 2017 | 527 | 2017 |
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression JJ Molenaar, R Domingo-Fernández, ME Ebus, S Lindner, J Koster, ... Nature genetics 44 (11), 1199-1206, 2012 | 436 | 2012 |
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus E Blasi, BJ Mathieson, L Varesio, JL Cleveland, PA Borchert, UR Rapp Nature 318 (6047), 667-670, 1985 | 322 | 1985 |
Regulation of human macrophage M1–M2 polarization balance by hypoxia and the triggering receptor expressed on myeloid cells-1 F Raggi, S Pelassa, D Pierobon, F Penco, M Gattorno, F Novelli, A Eva, ... Frontiers in immunology 8, 1097, 2017 | 301 | 2017 |
Hypoxia downregulates the expression of activating receptors involved in NK‐cell‐mediated target cell killing without affecting ADCC M Balsamo, C Manzini, G Pietra, F Raggi, F Blengio, MC Mingari, ... European journal of immunology 43 (10), 2756-2764, 2013 | 278 | 2013 |
Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine G Melillo, LS Taylor, A Brooks, T Musso, GW Cox, L Varesio Journal of Biological Chemistry 272 (18), 12236-12243, 1997 | 253 | 1997 |
Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid S Camandola, G Leonarduzzi, T Musso, L Varesio, R Carini, A Scavazza, ... Biochemical and biophysical research communications 229 (2), 643-647, 1996 | 249 | 1996 |
Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene MC Bosco, M Puppo, C Santangelo, L Anfosso, U Pfeffer, P Fardin, ... The Journal of immunology 177 (3), 1941-1955, 2006 | 233 | 2006 |
Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration MC Bosco, M Puppo, F Blengio, T Fraone, P Cappello, M Giovarelli, ... Immunobiology 213 (9-10), 733-749, 2008 | 229 | 2008 |
Interleukin-4 inhibits indoleamine 2, 3-dioxygenase expression in human monocytes T Musso, GL Gusella, A Brooks, DL Longo, L Varesio | 197 | 1994 |
The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma F Amoroso, M Capece, A Rotondo, D Cangelosi, M Ferracin, ... Oncogene 34 (41), 5240-5251, 2015 | 188 | 2015 |
Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. T Musso, JA Johnston, D Linnekin, L Varesio, TK Rowe, JJ O'shea, ... The Journal of experimental medicine 181 (4), 1425-1431, 1995 | 184 | 1995 |
Tumor necrosis factor-alpha-dependent production of reactive nitrogen intermediates mediates IFN-gamma plus IL-2-induced murine macrophage tumoricidal activity. GW Cox, G Melillo, U Chattopadhyay, D Mullet, RH Fertel, L Varesio Journal of immunology (Baltimore, Md.: 1950) 149 (10), 3290-3296, 1992 | 183 | 1992 |
Differential inhibition of IL-1 and TNF-alpha mRNA expression by agents which block second messenger pathways in murine macrophages. EJ Kovacs, D Radzioch, HA Young, L Varesio Journal of immunology (Baltimore, Md.: 1950) 141 (9), 3101-3105, 1988 | 183 | 1988 |
Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes G Melillo, EA Sausville, K Cloud, T Lahusen, L Varesio, AM Senderowicz Cancer Research 59 (21), 5433-5437, 1999 | 180 | 1999 |
Heterogeneity of hematopoietic cells immortalized by v-myc/v-raf recombinant retrovirus infection of bone marrow or fetal liver GW Cox, BJ Mathieson, L Gandino, E Blasi, D Radzioch, L Varesio JNCI: Journal of the National Cancer Institute 81 (19), 1492-1496, 1989 | 164 | 1989 |
Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway L Petecchia, F Sabatini, C Usai, E Caci, L Varesio, GA Rossi Laboratory investigation 92 (8), 1140-1148, 2012 | 161 | 2012 |
Regulation of nitric-oxide synthase mRNA expression by interferon-gamma and picolinic acid. G Melillo, GW Cox, A Biragyn, LA Sheffler, L Varesio Journal of Biological Chemistry 269 (11), 8128-8133, 1994 | 151 | 1994 |
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo MC Bosco, D Pierobon, F Blengio, F Raggi, C Vanni, M Gattorno, A Eva, ... Blood, The Journal of the American Society of Hematology 117 (9), 2625-2639, 2011 | 147 | 2011 |