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Ramon Ayon
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Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition
H Tang, A Babicheva, KM McDermott, Y Gu, RJ Ayon, S Song, Z Wang, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (2 …, 2018
1862018
Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series)
B Ranchoux, LD Harvey, RJ Ayon, A Babicheva, S Bonnet, SY Chan, ...
Pulmonary circulation 8 (1), 2045893217752912, 2018
1432018
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension
AS Forrest, TC Joyce, ML Huebner, RJ Ayon, M Wiwchar, J Joyce, ...
American Journal of Physiology-Cell Physiology 303 (12), C1229-C1243, 2012
1432012
PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension
Y Cao, X Zhang, L Wang, Q Yang, Q Ma, J Xu, J Wang, L Kovacs, ...
Proceedings of the National Academy of Sciences 116 (27), 13394-13403, 2019
1352019
SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery
Y Han, YE Cho, R Ayon, R Guo, KD Youssef, M Pan, A Dai, JXJ Yuan, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (9 …, 2015
1022015
Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2
J Wan, A Yamamura, AM Zimnicka, G Voiriot, KA Smith, H Tang, RJ Ayon, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 305 (2 …, 2013
982013
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension
H Tang, A Yamamura, H Yamamura, S Song, DR Fraidenburg, J Chen, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (9 …, 2016
822016
Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension
S Song, A Yamamura, H Yamamura, RJ Ayon, KA Smith, H Tang, ...
American Journal of Physiology-Cell Physiology 307 (4), C373-C383, 2014
752014
Calcium-sensing receptor regulates cytosolic [Ca2+] and plays a major role in the development of pulmonary hypertension
KA Smith, RJ Ayon, H Tang, A Makino, JXJ Yuan
Frontiers in Physiology 7, 221773, 2016
642016
Pathogenic role of mTORC1 and mTORC2 in pulmonary hypertension
H Tang, K Wu, J Wang, S Vinjamuri, Y Gu, S Song, Z Wang, Q Zhang, ...
JACC: Basic to Translational Science 3 (6), 744-762, 2018
532018
STIM2 (Stromal Interaction Molecule 2)–Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial …
S Song, SG Carr, KM McDermott, M Rodriguez, A Babicheva, A Balistrieri, ...
Hypertension 71 (3), 518-529, 2018
532018
Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension
K Wu, Q Zhang, X Wu, W Lu, H Tang, Z Liang, Y Gu, S Song, RJ Ayon, ...
British journal of pharmacology 174 (22), 4155-4172, 2017
532017
Molecular and Functional Significance of Ca2+-Activated Cl Channels in Pulmonary Arterial Smooth Muscle
N Leblanc, AS Forrest, RJ Ayon, M Wiwchar, JE Angermann, ...
Pulmonary circulation 5 (2), 244-268, 2015
482015
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension
Z Wang, K Yang, Q Zheng, C Zhang, H Tang, A Babicheva, Q Jiang, M Li, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 316 (1 …, 2019
462019
Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells
X He, S Song, RJ Ayon, A Balisterieri, SM Black, A Makino, WG Wier, ...
American Journal of Physiology-Cell Physiology 314 (4), C504-C517, 2018
402018
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH
S Song, RJ Ayon, A Yamamura, H Yamamura, S Dash, A Babicheva, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (3 …, 2017
362017
Phosphorylation alters the pharmacology of Ca2+‐activated Cl channels in rabbit pulmonary arterial smooth muscle cells
M Wiwchar, R Ayon, IA Greenwood, N Leblanc
British journal of pharmacology 158 (5), 1356-1365, 2009
332009
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension
Z Wang, J Chen, A Babicheva, PP Jain, M Rodriguez, RJ Ayon, ...
American Journal of Physiology-Cell Physiology 321 (6), C1010-C1027, 2021
322021
MicroRNA-mediated downregulation of K+ channels in pulmonary arterial hypertension
A Babicheva, RJ Ayon, T Zhao, JF Ek Vitorin, NM Pohl, A Yamamura, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (1 …, 2020
322020
Functional characterization of voltage-dependent Ca2+ channels in mouse pulmonary arterial smooth muscle cells: divergent effect of ROS
EA Ko, J Wan, A Yamamura, AM Zimnicka, H Yamamura, HY Yoo, H Tang, ...
American Journal of Physiology-Cell Physiology 304 (11), C1042-C1052, 2013
242013
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