|Phosphoinositide-3-kinase catalytic alpha and KRAS mutations are important predictors of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors …|
V Ludovini, F Bianconi, L Pistola, R Chiari, V Minotti, R Colella, D Giuffrida, ...
Journal of thoracic oncology 6 (4), 707-715, 2011
|The KRASG12C inhibitor MRTX849 provides insight toward therapeutic susceptibility of KRAS-mutant cancers in mouse models and patients|
J Hallin, LD Engstrom, L Hargis, A Calinisan, R Aranda, DM Briere, ...
Cancer discovery 10 (1), 54-71, 2020
|Multiclass HCV resistance to direct‐acting antiviral failure in real‐life patients advocates for tailored second‐line therapies|
VC Di Maio, V Cento, I Lenci, M Aragri, P Rossi, S Barbaliscia, M Melis, ...
Liver International 37 (4), 514-528, 2017
|Association of cytidine deaminase and xeroderma pigmentosum group D polymorphisms with response, toxicity, and survival in cisplatin/gemcitabine-treated advanced non-small cell …|
V Ludovini, I Floriani, L Pistola, V Minotti, M Meacci, R Chiari, ...
Journal of thoracic oncology 6 (12), 2018-2026, 2011
|Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations|
V Ludovini, F Bianconi, L Pistola, V Minotti, R Chiari, R Colella, ...
Cancer chemotherapy and pharmacology 69 (5), 1289-1299, 2012
|Computational model of EGFR and IGF1R pathways in lung cancer: a systems biology approach for translational oncology|
F Bianconi, E Baldelli, V Ludovini, L Crino, A Flacco, P Valigi
Biotechnology advances 30 (1), 142-153, 2012
|Functional characterization of epithelial ovarian cancer histotypes by drug target based protein signaling activation mapping: implications for personalized cancer therapy|
MI Sereni, E Baldelli, G Gambara, J Deng, L Zanotti, E Bandiera, ...
Proteomics 15 (2-3), 365-373, 2015
|Impact of upfront cellular enrichment by laser capture microdissection on protein and phosphoprotein drug target signaling activation measurements in human lung cancer …|
E Baldelli, EB Haura, L Crinò, DW Cress, V Ludovini, MB Schabath, ...
PROTEOMICS–Clinical Applications 9 (9-10), 928-937, 2015
|Concomitant high gene copy number and protein overexpression of IGF1R and EGFR negatively affect disease-free survival of surgically resected non-small-cell-lung cancer patients|
V Ludovini, A Flacco, F Bianconi, M Ragusa, J Vannucci, G Bellezza, ...
Cancer chemotherapy and pharmacology 71 (3), 671-680, 2013
|Reverse phase protein microarrays|
E Baldelli, V Calvert, A Hodge, A VanMeter, EF Petricoin, M Pierobon
Molecular profiling, 149-169, 2017
|Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors|
E Baldelli, G Bellezza, EB Haura, L Crinó, WD Cress, J Deng, V Ludovini, ...
Oncotarget 6 (32), 32368, 2015
|The sustained induction of c-MYC drives nab-paclitaxel resistance in primary pancreatic ductal carcinoma cells|
E Parasido, GS Avetian, A Naeem, G Graham, M Pishvaian, E Glasgow, ...
Molecular Cancer Research 17 (9), 1815-1827, 2019
|A pilot study exploring the molecular architecture of the tumor microenvironment in human prostate cancer using laser capture microdissection and reverse phase protein microarray|
E Pin, S Stratton, C Belluco, L Liotta, R Nagle, KA Hodge, J Deng, T Dong, ...
Molecular oncology 10 (10), 1585-1594, 2016
|HCV NS3 sequencing as a reliable and clinically useful tool for the assessment of genotype and resistance mutations for clinical samples with different HCV-RNA levels|
VC Di Maio, V Cento, D Di Paolo, M Aragri, F De Leonardis, ...
Journal of Antimicrobial Chemotherapy 71 (3), 739-750, 2016
|Conditional robustness analysis for fragility discovery and target identification in biochemical networks and in cancer systems biology|
F Bianconi, E Baldelli, V Luovini, EF Petricoin, L Crino, P Valigi
BMC systems biology 9 (1), 70, 2015
|Robustness of complex feedback systems: application to oncological biochemical networks|
F Bianconi, E Baldelli, V Ludovini, L Crinò, K Perruccio, P Valigi
International Journal of Control 86 (7), 1304-1321, 2013
|Kinase-driven metabolic signalling as a predictor of response to carboplatin–paclitaxel adjuvant treatment in advanced ovarian cancers|
MI Sereni, E Baldelli, G Gambara, A Ravaggi, KA Hodge, DS Alberts, ...
British journal of cancer 117 (4), 494-502, 2017
|Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of MET, EGFR, KRAS, and PIK3CA mutations.|
V Ludovini, F Bianconi, L Pistola, R Chiari, FR Tofanetti, A Siggillino, ...
Journal of Clinical Oncology 28 (15_suppl), 7562-7562, 2010
|Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non-small cell lung cancer (NSCLC): a pilot study|
V Ludovini, R Chiari, L Tomassoni, C Antonini, E Baldelli, S Baglivo, ...
Oncotarget 8 (47), 83343, 2017
|Quantitative measurement of PDL1 expression across tumor types using laser capture microdissection and reverse phase protein microarray|
E Baldelli, V Calvert, KA Hodge, MI Sereni, G Gambara, EB Haura, ...
Cancer Research 77 (13 Supplement), 5656-5656, 2017