|NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings|
O An, GM Dall'Olio, TP Mourikis, FD Ciccarelli
Nucleic acids research 44 (D1), D992-D999, 2016
|NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes|
O An, V Pendino, M D’Antonio, E Ratti, M Gentilini, FD Ciccarelli
Database 2014, 2014
|Super-enhancer-driven long non-coding RNA LINC01503, regulated by TP63, is over-expressed and oncogenic in squamous cell carcinoma|
JJ Xie, YY Jiang, Y Jiang, CQ Li, MC Lim, O An, A Mayakonda, LW Ding, ...
Gastroenterology 154 (8), 2137-2151. e1, 2018
|Structural and functional analysis of perforin mutations in association with clinical data of familial hemophagocytic lymphohistiocytosis type 2 (FHL2) patients|
O An, A Gursoy, A Gurgey, O Keskin
Protein Science 22 (6), 823-839, 2013
|MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles|
QX Xuan Lin, S Sian, O An, D Thieffry, S Jha, T Benoukraf
Nucleic acids research 47 (D1), D145-D154, 2019
|Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers|
R Kumar, L Coronel, B Somalanka, A Raju, OA Aning, O An, YS Ho, ...
Nature communications 9 (1), 1-13, 2018
|Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis|
PJ Teoh, O An, TH Chung, JY Chooi, SHM Toh, S Fan, W Wang, BTH Koh, ...
Blood, The Journal of the American Society of Hematology 132 (12), 1304-1317, 2018
|The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia|
SH Tan, WZ Leong, PCT Ngoc, TK Tan, FC Bertulfo, MC Lim, O An, Z Li, ...
blood 134 (3), 239-251, 2019
|Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer|
HQ Hong, O An, THM Chan, VHE Ng, HS Kwok, JS Lin, L Qi, J Han, ...
Nucleic acids research 46 (15), 7953-7969, 2018
|Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma|
L Chen, M Huang, J Plummer, J Pan, YY Jiang, Q Yang, TC Silva, N Gull, ...
Gut 69 (4), 630-640, 2020
|CSI NGS portal: an online platform for automated ngs data analysis and sharing|
O An, KT Tan, Y Li, J Li, CS Wu, B Zhang, L Chen, H Yang
International Journal of Molecular Sciences 21 (11), 3828, 2020
|Mitochondrial 3243A> G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells|
NMQ Pek, QH Phua, BX Ho, JKS Pang, JH Hor, O An, HH Yang, Y Yu, ...
Cell death & disease 10 (11), 1-16, 2019
|Cis-and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development|
SJ Tang, H Shen, O An, HQ Hong, J Li, Y Song, J Han, DJT Tay, VHE Ng, ...
Nature communications 11 (1), 1-17, 2020
|Identification of a novel enhancer of CEBPE essential for granulocytic differentiation|
P Shyamsunder, M Shanmugasundaram, A Mayakonda, P Dakle, ...
Blood, The Journal of the American Society of Hematology 133 (23), 2507-2517, 2019
|Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias|
ZT Lao, LW Ding, O An, N Hattori, QY Sun, KT Tan, A Mayakonda, ...
|Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression|
J Han, O An, HQ Hong, THM Chan, Y Song, H Shen, SJ Tang, JS Lin, ...
Science Advances 6 (25), eaba5136, 2020
|"3G" Trial: An RNA Editing Signature for Guiding Gastric Cancer Chemotherapy|
O An, Y Song, X Ke, JBY So, R Sundar, H Yang, SY Rha, LM Hui, TS Ting, ...
|HNRNPM controls circRNA biogenesis and splicing fidelity to sustain prostate cancer cell fitness|
SYJ Ho, D Low, M Schwarz, D Incarnato, F Gay, T Tabaglio, JX Zhang, ...
|Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia|
B Wang, L Kong, D Babu, R Choudhary, W Fam, JQ Tng, Y Goh, X Liu, ...
|Synthetic lethality in multiple myeloma harboring double oncogenic hits of 17p13 (del) and 1q21 (amp)|
PJ Teoh, TH Chung, O An, P Chng, A Jeyasekharan, H Yang, WJ Chng
Clinical Lymphoma, Myeloma and Leukemia 19 (10), e50-e51, 2019