| Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. Y Kubota, RA Nash, A Klungland, P Schär, DE Barnes, T Lindahl The EMBO journal 15 (23), 6662-6670, 1996 | 1065 | 1996 |
| DNA glycosylases: in DNA repair and beyond AL Jacobs, P Schär Chromosoma 121, 1-20, 2012 | 472 | 2012 |
| Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability D Cortázar, C Kunz, J Selfridge, T Lettieri, Y Saito, E MacDougall, A Wirz, ... Nature 470 (7334), 419-423, 2011 | 434 | 2011 |
| Modification of the human thymine‐DNA glycosylase by ubiquitin‐like proteins facilitates enzymatic turnover U Hardeland, R Steinacher, J Jiricny, P Schär The EMBO journal, 2002 | 398 | 2002 |
| Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA T Pfaffeneder, F Spada, M Wagner, C Brandmayr, SK Laube, D Eisen, ... Nature chemical biology 10 (7), 574-581, 2014 | 325 | 2014 |
| Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination YF Wei, P Robins, K Carter, K Caldecott, DJC Pappin, GL Yu, RP Wang, ... Molecular and cellular biology 15 (6), 3206-3216, 1995 | 322 | 1995 |
| NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae M Valencia, M Bentele, MB Vaze, G Herrmann, E Kraus, SE Lee, P Schär, ... Nature 414 (6864), 666-669, 2001 | 279 | 2001 |
| A newly identified DNA ligase of Saccharomyces cerevisiaeinvolved in RAD52-independent repair of DNA double-strand breaks P Schär, G Herrmann, G Daly, T Lindahl Genes & development 11 (15), 1912-1924, 1997 | 247 | 1997 |
| Identification of hMutLβ, a heterodimer of hMLH1 and hPMS1 M Räschle, G Marra, M Nyström-Lahti, P Schär, J Jiricny Journal of Biological Chemistry 274 (45), 32368-32375, 1999 | 237 | 1999 |
| The enigmatic thymine DNA glycosylase D Cortázar, C Kunz, Y Saito, R Steinacher, P Schär DNA repair 6 (4), 489-504, 2007 | 236 | 2007 |
| Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer K Truninger, M Menigatti, J Luz, A Russell, R Haider, JO Gebbers, ... Gastroenterology 128 (5), 1160-1171, 2005 | 223 | 2005 |
| Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism AR Weber, C Krawczyk, AB Robertson, A Kuśnierczyk, CB Vågbø, ... Nature communications 7 (1), 10806, 2016 | 220 | 2016 |
| Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation R Steinacher, P Schär Current Biology 15 (7), 616-623, 2005 | 217 | 2005 |
| Arginine methylation regulates DNA polymerase β N El-Andaloussi, T Valovka, M Toueille, R Steinacher, F Focke, P Gehrig, ... Molecular cell 22 (1), 51-62, 2006 | 216 | 2006 |
| Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4 G Herrmann, T Lindahl, P Schär The EMBO journal 17 (14), 4188-4198, 1998 | 216 | 1998 |
| DNA fragmentation in human fibroblasts under extremely low frequency electromagnetic field exposure F Focke, D Schuermann, N Kuster, P Schär Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 683 (1 …, 2010 | 179 | 2010 |
| The versatile thymine DNA‐glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs U Hardeland, M Bentele, J Jiricny, P SchaČr Nucleic acids research 31 (9), 2261-2271, 2003 | 176 | 2003 |
| Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil C Kunz, F Focke, Y Saito, D Schuermann, T Lettieri, J Selfridge, P Schär PLoS biology 7 (4), e1000091, 2009 | 161 | 2009 |
| Spontaneous DNA damage, genome instability, and cancer—when DNA replication escapes control P Schär Cell 104 (3), 329-332, 2001 | 153 | 2001 |
| Recognition of DNA alterations by the mismatch repair system G MARRA, P Schär Biochemical Journal 338 (1), 1-13, 1999 | 153 | 1999 |
David SchuermannUniversity of Basel, Department of BiomedicineVerified email at unibas.ch
