Alejandro Schaffer

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Webb MillerPenn State University, UC Santa Barbara, ArizonaVerified email at bx.psu.edu
Stephen AltschulNCBI NLM NIHVerified email at nih.gov
Bodo GrimbacherProfessor of Immunology, Albert-Ludwigs University Freiburg, GermanyVerified email at uniklinik-freiburg.de
Thomas L. MaddenStaff Scientist, NCBI, NLM, NIHVerified email at ncbi.nlm.nih.gov
Eytan RuppinChief, Cancer Data Science Lab (CDSL), NCI/NIHVerified email at nih.gov
Stephen J. O'BrienNova Southeastern University, Ft. Lauderdale FL.Verified email at nova.edu
Russell SchwartzProfessor of Biological Sciences and Computational Biology, Carnegie Mellon UniversityVerified email at andrew.cmu.edu
Jinghui ZhangSt Jude Children's Research HospitalVerified email at stjude.org
Sanju SinhaNational Cancer InstituteVerified email at terpmail.umd.edu
Lennart HammarstromProfessor i Klinisk Immunologi, Karolinska InstitutetVerified email at ki.se
Alessandro PlebaniUniversità di BresciaVerified email at unibs.it
Klaus WarnatzDep. of Rheumatology and Clinical Immunology, CCI, University Medical Center Freiburg, FreiburgVerified email at uniklinik-freiburg.de
Ariel Israel, MD, PhDDirector, Leumit Research InstituteVerified email at mail.huji.ac.il
Nima RezaeiTehran University of Medical Sciences; Universal Scientific Education and Research Network (USERN)Verified email at tums.ac.ir
Salim Akhter ChowdhuryFlatiron Institute, Princeton UniversityVerified email at princeton.edu
Bob CottinghamOak Ridge National LaboratoryVerified email at ornl.gov
Yi-Kuo YuSenior Investigator, NCBI/NLM/NIHVerified email at ncbi.nlm.nih.gov
Eugene MerzonAssociate Professor, The Adelson School of Medicine, Ariel University; Leumit Health Services;Verified email at leumit.co.il
Avivit Golan Cohenמרצה, אוניברסיטת תל אביבVerified email at leumit.co.il
Clair FrancomanoIndiana University School of MedicineVerified email at iu.edu

Alejandro Schaffer

Computer Scientist, National Institutes of Health

Verified email at nih.gov - Homepage

Bioinformatics Cancer Algorithms Medical Genetics Immunology


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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs SF Altschul, TL Madden, AA Schäffer, J Zhang, Z Zhang, W Miller, ... Nucleic acids research 25 (17), 3389-3402, 1997	88632	1997
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor EO Glocker, D Kotlarz, K Boztug, EM Gertz, AA Schäffer, F Noyan, M Perro, ... New England Journal of Medicine 361 (21), 2033-2045, 2009	1746	2009
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements AA Schäffer, L Aravind, TL Madden, S Shavirin, JL Spouge, YI Wolf, ... Nucleic acids research 29 (14), 2994-3005, 2001	1688	2001
Faster sequential genetic linkage computations RW Cottingham Jr, RM Idury, AA Schäffer American journal of human genetics 53 (1), 252, 1993	1595	1993
Database indexing for production MegaBLAST searches A Morgulis, G Coulouris, Y Raytselis, TL Madden, R Agarwala, ... Bioinformatics 24 (16), 1757-1764, 2008	1515	2008
STAT3 mutations in the hyper-IgE syndrome SM Holland, FR DeLeo, HZ Elloumi, AP Hsu, G Uzel, N Brodsky, ... New England Journal of Medicine 357 (16), 1608-1619, 2007	1443	2007
Protein database searches using compositionally adjusted substitution matrices SF Altschul, JC Wootton, EM Gertz, R Agarwala, A Morgulis, AA Schäffer, ... The FEBS journal 272 (20), 5101-5109, 2005	1387	2005
Mapping of a gene for Parkinson's disease to chromosome 4q21-q23 MH Polymeropoulos, JJ Higgins, LI Golbe, WG Johnson, SE Ide, ... Science 274 (5290), 1197-1199, 1996	1166	1996
Domain enhanced lookup time accelerated BLAST GM Boratyn, AA Schäffer, R Agarwala, SF Altschul, DJ Lipman, ... Biology direct 7, 1-14, 2012	931	2012
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations D Schubert, C Bode, R Kenefeck, TZ Hou, JB Wing, A Kennedy, ... Nature medicine 20 (12), 1410-1416, 2014	921	2014
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency B Grimbacher, A Hutloff, M Schlesier, E Glocker, K Warnatz, R Dräger, ... Nature immunology 4 (3), 261-268, 2003	911	2003
A homozygous CARD9 mutation in a family with susceptibility to fungal infections EO Glocker, A Hennigs, M Nabavi, AA Schäffer, C Woellner, U Salzer, ... New England Journal of Medicine 361 (18), 1727-1735, 2009	901	2009
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans U Salzer, HM Chapel, ADB Webster, Q Pan-Hammarström, ... Nature genetics 37 (8), 820-828, 2005	820	2005
Avoiding recomputation in linkage analysis AA Schaeffer, SK Gupta, K Shriram, RW Cottingham, Jr Human heredity 44 (4), 225-237, 1994	794	1994
Graph spanners D Peleg, AA Schäffer Journal of graph theory 13 (1), 99-116, 1989	790	1989
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease) C Klein, M Grudzien, G Appaswamy, M Germeshausen, I Sandrock, ... Nature genetics 39 (1), 86-92, 2007	603	2007
A genetic linkage map of microsatellites in the domestic cat (Felis catus) M Menotti-Raymond, VA David, LA Lyons, AA Schäffer, JF Tomlin, ... Genomics 57 (1), 9-23, 1999	590	1999
Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity G Lopez-Herrera, G Tampella, Q Pan-Hammarström, P Herholz, ... The American Journal of Human Genetics 90 (6), 986-1001, 2012	588	2012
Composition-based statistics and translated nucleotide searches: improving the TBLASTN module of BLAST EM Gertz, YK Yu, R Agarwala, AA Schäffer, SF Altschul BMC biology 4, 1-14, 2006	572	2006
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25. 2-27 H Matsumine, M Saito, S Shimoda-Matsubayashi, H Tanaka, A Ishikawa, ... American journal of human genetics 60 (3), 588, 1997	570	1997

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