High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress M Balakumar, L Raji, D Prabhu, C Sathishkumar, P Prabu, V Mohan, ... Molecular and cellular biochemistry 423, 93-104, 2016 | 118 | 2016 |
Gallic acid protects RINm5F β‐cells from glucolipotoxicity by its antiapoptotic and insulin‐secretagogue actions Z Sameermahmood, L Raji, T Saravanan, A Vaidya, V Mohan, ... Phytotherapy Research 24 (S1), S83-S94, 2010 | 90 | 2010 |
Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes C Sathishkumar, P Prabu, M Balakumar, R Lenin, D Prabhu, RM Anjana, ... Clinical epigenetics 8, 1-12, 2016 | 74 | 2016 |
Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities S SantaCruz-Calvo, L Bharath, G Pugh, L SantaCruz-Calvo, RR Lenin, ... Nature Reviews Endocrinology 18 (1), 23-42, 2022 | 64 | 2022 |
Concentrated conditioned media from adipose tissue derived mesenchymal stem cells mitigates visual deficits and retinal inflammation following mild traumatic brain injury KA Jha, M Pentecost, R Lenin, L Klaic, SL Elshaer, J Gentry, JM Russell, ... International journal of molecular sciences 19 (7), 2016, 2018 | 59 | 2018 |
Altered immunometabolism at the interface of increased endoplasmic reticulum (ER) stress in patients with type 2 diabetes R Lenin, A Sankaramoorthy, V Mohan, M Balasubramanyam Journal of Leucocyte Biology 98 (4), 615-622, 2015 | 59 | 2015 |
TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, ... Stem cell research & therapy 10, 1-15, 2019 | 46 | 2019 |
Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse SL Elshaer, W Evans, M Pentecost, R Lenin, R Periasamy, KA Jha, S Alli, ... Stem Cell Research & Therapy 9, 1-18, 2018 | 45 | 2018 |
Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a “chemical chaperone” in human THP-1 monocytes R Lenin, MS Maria, M Agrawal, J Balasubramanyam, V Mohan, ... Journal of Diabetes Research 2012, 2012 | 34 | 2012 |
Endoplasmic reticulum stress in diabetes: New insights of clinical relevance M Balasubramanyam, R Lenin, F Monickaraj Indian journal of clinical biochemistry 25, 111-118, 2010 | 28 | 2010 |
GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability R Lenin, PG Nagy, KA Jha, R Gangaraju Scientific reports 9 (1), 10783, 2019 | 27 | 2019 |
Endothelial activation and oxidative stress in neurovascular defects of the retina R Lenin, SM Thomas, R Gangaraju Current pharmaceutical design 24 (40), 4742-4754, 2018 | 25 | 2018 |
Critical role of endoplasmic reticulum stress in chronic endothelial activation− induced visual deficits in tie2‐tumor necrosis factor mice R Lenin, PG Nagy, S Alli, VR Rao, MA Clauss, UB Kompella, R Gangaraju Journal of cellular biochemistry 119 (10), 8460-8471, 2018 | 19 | 2018 |
Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice R Lenin, PG Nagy, J Gentry, R Gangaraju Experimental Biology and Medicine 243 (12), 976-984, 2018 | 6 | 2018 |
Tauroursodeoxycholic acid alleviates endoplasmic reticulum stress-mediated visual deficits in diabetic tie2-TNF transgenic mice via TGR5 signaling R Lenin, KA Jha, J Gentry, A Shrestha, EV Culp, T Vaithianathan, ... Journal of Ocular Pharmacology and Therapeutics 39 (2), 159-174, 2023 | 5 | 2023 |
Dysfunctional Autophagy, Proteostasis, and Mitochondria as a Prelude to Age-Related Macular Degeneration RR Lenin, HK Yi, Z Zheting, ZY Yan, HP Bhav, S Ivan, W Wendy, S Xinyi Int J Mol Sci 24 (10), 8763, 2023 | 4 | 2023 |
SEAP activity serves for demonstrating ER stress induction by glucolipotoxicity as well as testing ER stress inhibitory potential of therapeutic agents R Lenin, V Mohan, M Balasubramanyam Molecular and Cellular Biochemistry 404, 271-279, 2015 | 4 | 2015 |
Mitochondria-Associated Membranes Are Not Altered In Immune Cells In T2D SN Hart, R Lenin, J Sturgill, PA Kern, BS Nikolajczyk bioRxiv, 2024.03. 25.586170, 2024 | | 2024 |
FGF4 alleviates hyperglycemia in diabetes and obesity conditions SM Sundaram, RR Lenin, R Janardhanan Trends in Endocrinology & Metabolism, 2023 | | 2023 |
TGR5 mediated action of tauroursodeoxycholic acid ameliorates endoplasmic reticulum stress-associated permeability in activated human retinal endothelial cells R Gangaraju, RR Lenin, J Gentry Investigative Ophthalmology & Visual Science 61 (7), 1765-1765, 2020 | | 2020 |