Ken Prehoda
Ken Prehoda
Professor of Chemistry, University of Oregon
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Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
BJ Hillier, KS Christopherson, KE Prehoda, DS Bredt, WA Lim
Science 284 (5415), 812-815, 1999
Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex
KE Prehoda, JA Scott, RD Mullins, WA Lim
Science 290 (5492), 801-806, 2000
The CXXC motif: a rheostat in the active site
PT Chivers, KE Prehoda, RT Raines
Biochemistry 36 (14), 4061-4066, 1997
Structure of the enabled/VASP homology 1 domain–peptide complex: a key component in the spatial control of actin assembly
KE Prehoda, DJ Lee, WA Lim
Cell 97 (4), 471-480, 1999
Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins
AW McGee, SR Dakoji, O Olsen, DS Bredt, WA Lim, KE Prehoda
Molecular cell 8 (6), 1291-1301, 2001
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells
CA Johnston, K Hirono, KE Prehoda, CQ Doe
Cell 138 (6), 1150-1163, 2009
A polybasic motif allows N-WASP to act as a sensor of PIP2 density
V Papayannopoulos, KE Prehoda, S Snapper, J Taunton, WA Lim
Molecular cell 17 (2), 181-191, 2005
Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome
BF Volkman, KE Prehoda, JA Scott, FC Peterson, WA Lim
Cell 111 (4), 565-576, 2002
Microscopic p K a values of Escherichia coli thioredoxin
PT Chivers, KE Prehoda, BF Volkman, BM Kim, JL Markley, RT Raines
Biochemistry 36 (48), 14985-14991, 1997
aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division
SX Atwood, KE Prehoda
Current Biology 19 (9), 723-729, 2009
Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition
FC Peterson, RR Penkert, BF Volkman, KE Prehoda
Molecular cell 13 (5), 665-676, 2004
A spindle-independent cleavage furrow positioning pathway
C Cabernard, KE Prehoda, CQ Doe
Nature 467 (7311), 91-94, 2010
Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6–aPKC
SX Atwood, C Chabu, RR Penkert, CQ Doe, KE Prehoda
Journal of cell science 120 (18), 3200-3206, 2007
Internal recognition through PDZ domain plasticity in the Par-6–Pals1 complex
RR Penkert, HM DiVittorio, KE Prehoda
Nature structural & molecular biology 11 (11), 1122-1127, 2004
Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy
CA Royer, AP Hinck, SN Loh, KE Prehoda, X Peng, J Jonas, JL Markley
Biochemistry 32 (19), 5222-5232, 1993
The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish
M Ségalen, CA Johnston, CA Martin, JG Dumortier, KE Prehoda, ...
Developmental cell 19 (5), 740-752, 2010
Polarization of Drosophila neuroblasts during asymmetric division
KE Prehoda
Cold Spring Harbor perspectives in biology 1 (2), a001388, 2009
Hydrogen exchange in unligated and ligated staphylococcal nuclease
SN Loh, KE Prehoda, J Wang, JL Markley
Biochemistry 32 (41), 11022-11028, 1993
Gαi generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts
RW Nipper, KH Siller, NR Smith, CQ Doe, KE Prehoda
Proceedings of the National Academy of Sciences 104 (36), 14306-14311, 2007
Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement
C Graybill, B Wee, SX Atwood, KE Prehoda
Journal of Biological Chemistry 287 (25), 21003-21011, 2012
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