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Summer Thyme
Summer Thyme
Unknown affiliation
Verified email at umassmed.edu - Homepage
Title
Cited by
Cited by
Year
Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs
JA Gagnon, E Valen, SB Thyme, P Huang, L Ahkmetova, A Pauli, ...
PloS one 9 (5), e98186, 2014
9802014
CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering
K Labun, TG Montague, JA Gagnon, SB Thyme, E Valen
Nucleic acids research 44 (W1), W272-W276, 2016
9512016
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5602020
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
N Windbichler, M Menichelli, PA Papathanos, SB Thyme, H Li, UY Ulge, ...
Nature 473 (7346), 212-215, 2011
4082011
Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions
SB Thyme, LM Pieper, EH Li, S Pandey, Y Wang, NS Morris, C Sha, ...
Cell 177 (2), 478-491. e20, 2019
1712019
Internal guide RNA interactions interfere with Cas9-mediated cleavage
SB Thyme, L Akhmetova, TG Montague, E Valen, AF Schier
Nature communications 7 (1), 11750, 2016
1662016
Kctd13 deletion reduces synaptic transmission via increased RhoA
CO Escamilla, I Filonova, AK Walker, ZX Xuan, R Holehonnur, F Espinosa, ...
Nature 551 (7679), 227-231, 2017
1452017
Exploitation of binding energy for catalysis and design
SB Thyme, J Jarjour, R Takeuchi, JJ Havranek, J Ashworth, ...
Nature 461 (7268), 1300-1304, 2009
1102009
Polq-mediated end joining is essential for surviving DNA double-strand breaks during early zebrafish development
SB Thyme, AF Schier
Cell reports 15 (4), 707-714, 2016
842016
Mechanistic Study of Competitive sp3-sp3 and sp2-sp3 Carbon-Carbon Reductive Elimination from a Platinum (IV) Center and the Isolation of a CC Agostic Complex
L Brian, B Summer, S Keene, BS Williams
Journal of the American Chemical Society 129 (31), 9538-9539, 2007
572007
Reprogramming homing endonuclease specificity through computational design and directed evolution
SB Thyme, SJS Boissel, S Arshiya Quadri, T Nolan, DA Baker, RU Park, ...
Nucleic acids research 42 (4), 2564-2576, 2014
362014
Improved modeling of side-chain–base interactions and plasticity in protein–DNA interface design
SB Thyme, D Baker, P Bradley
Journal of molecular biology 419 (3-4), 255-274, 2012
212012
Massively parallel determination and modeling of endonuclease substrate specificity
SB Thyme, Y Song, TJ Brunette, MD Szeto, L Kusak, P Bradley, D Baker
Nucleic acids research 42 (22), 13839-13852, 2014
162014
Mining endonuclease cleavage determinants in genomic sequence data
MD Szeto, SJS Boissel, D Baker, SB Thyme
Journal of Biological Chemistry 286 (37), 32617-32627, 2011
162011
A customizable low-cost system for massively parallel zebrafish behavioral phenotyping
W Joo, MD Vivian, BJ Graham, ER Soucy, SB Thyme
Frontiers in Behavioral Neuroscience 14, 606900, 2021
132021
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
Y Wang, IF Khan, S Boissel, J Jarjour, J Pangallo, S Thyme, D Baker, ...
Nucleic Acids Research 42 (10), 6463-6475, 2014
122014
Redesigning the specificity of protein–DNA interactions with Rosetta
S Thyme, D Baker
Homing Endonucleases: Methods and Protocols, 265-282, 2014
122014
Mosaic and non-mosaic protocadherin 19 mutation leads to neuronal hyperexcitability in zebrafish
BK Robens, X Yang, CM McGraw, LH Turner, C Robens, S Thyme, ...
Neurobiology of disease 169, 105738, 2022
92022
A single-cell transcriptome atlas of the maturing zebrafish telencephalon
S Pandey, AJ Moyer, SB Thyme
Genome Research 33 (4), 658-671, 2023
82023
Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition
JU Park, MT Petassi, SC Hsieh, E Mehrotra, G Schuler, J Budhathoki, ...
Molecular Cell 83 (11), 1827-1838. e6, 2023
42023
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