James Costello

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Gustavo StolovitzkyDirector, Biomed Data Sciences Hub, NYU Langone Health; Prof. Pathology Dep, NYU School of MedicineVerified email at nyulangone.org
James J CollinsMIT; Wyss Institute, Harvard; Broad Institute of MIT & HarvardVerified email at mit.edu
Robert J. PrillIBM ResearchVerified email at us.ibm.com
Julio Saez RodriguezHeidelberg UniversityVerified email at uni-heidelberg.de
Mukesh BansalBristol Myers SquibbVerified email at bms.com
Daniel MarbachRoche Pharma Research and Early Development, Basel, SwitzerlandVerified email at roche.com
Garrett DancikProfessor, Eastern Connecticut State UniversityVerified email at easternct.edu
Laura HeiserAssociate Professor, Oregon Health and Science UniversityVerified email at ohsu.edu
Kyle R AllisonEmory UniversityVerified email at emory.edu
Manolis KellisProfessor of Computer Science, MIT and Broad InstituteVerified email at mit.edu
Lawrence KwongMD Anderson Cancer CenterVerified email at mdanderson.org
Mehmet GönenProfessor of Industrial Engineering and Computational Biology, Koç UniversityVerified email at ku.edu.tr
Yang XieProfessor, UT Southwestern Medical CenterVerified email at utsouthwestern.edu
Thomas R. CechDistinguished Professor, Department of Chemistry and Biochemistry, University of Colorado BoulderVerified email at colorado.edu
Joe GrayBiomedical Engineering, Oregon Health and Science UniversityVerified email at ohsu.edu
Pablo MeyerResearch Staff Member, IBMVerified email at us.ibm.com
Joaquin M. EspinosaExecutive Director, Linda Crnic Institute for Down Syndrome, University of ColoradoVerified email at cuanschutz.edu
Kelly D. SullivanAssociate Professor - Linda Crnic Institute for Down Syndrome - CU AnschutzVerified email at colorado.edu
Suleiman Ali KhanAmazonVerified email at amazon.com
Antti HonkelaProfessor, University of HelsinkiVerified email at helsinki.fi

James Costello

University of Colorado Anschutz Medical Campus

Verified email at ucdenver.edu - Homepage

Cancer Systems Biology Functional Genomics Network Inference Data Integration


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Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-18, 2007	2286	2007
Wisdom of crowds for robust gene network inference D Marbach, JC Costello, R Küffner, NM Vega, RJ Prill, DM Camacho, ... Nature methods 9 (8), 796-804, 2012	1875	2012
Next-generation machine learning for biological networks DM Camacho, KM Collins, RK Powers, JC Costello, JJ Collins Cell 173 (7), 1581-1592, 2018	961	2018
A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014	816	2014
Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in mammalian cells S Kalghatgi, CS Spina, JC Costello, M Liesa, JR Morones-Ramirez, ... Science translational medicine 5 (192), 192ra85-192ra85, 2013	615	2013
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks D Malhotra, AL Fletcher, J Astarita, V Lukacs-Kornek, P Tayalia, ... Nature immunology 13 (5), 499-510, 2012	495	2012
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020	408	2020
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma LN Kwong, JC Costello, H Liu, S Jiang, TL Helms, AE Langsdorf, ... Nature medicine 18 (10), 1503-1510, 2012	401	2012
TERT promoter mutations and telomerase reactivation in urothelial cancer S Borah, L Xi, AJ Zaug, NM Powell, GM Dancik, SB Cohen, JC Costello, ... Science 347 (6225), 1006-1010, 2015	359	2015
Tumor-derived cell lines as molecular models of cancer pharmacogenomics A Goodspeed, LM Heiser, JW Gray, JC Costello Molecular Cancer Research 14 (1), 3-13, 2016	354	2016
A community computational challenge to predict the activity of pairs of compounds M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ... Nature biotechnology 32 (12), 1213-1222, 2014	344	2014
Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes K Narayan, KE Sylvia, N Malhotra, CC Yin, G Martens, T Vallerskog, ... Nature immunology 13 (5), 511-518, 2012	231	2012
GSEA-InContext: identifying novel and common patterns in expression experiments RK Powers, A Goodspeed, H Pielke-Lombardo, AC Tan, JC Costello Bioinformatics 34 (13), i555-i564, 2018	207	2018
Crowdsourcing biomedical research: leveraging communities as innovation engines J Saez-Rodriguez, JC Costello, SH Friend, MR Kellen, L Mangravite, ... Nature Reviews Genetics 17 (8), 470-486, 2016	177	2016
Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open … J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ... The Lancet Oncology 18 (1), 132-142, 2017	169	2017
Consortium D, Kellis M, Collins JJ, Stolovitzky G. Wisdom of crowds for robust gene network inference D Marbach, JC Costello, R Kuffner, NM Vega, RJ Prill, DM Camacho, ... Nat Methods 9 (8), 796-804, 2012	165	2012
“Reverse ecology” and the power of population genomics YF Li, JC Costello, AK Holloway, MW Hahn Evolution 62 (12), 2984-2994, 2008	158	2008
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy MM Tu, HA Abdel-Hafiz, RT Jones, A Jean, KJ Hoff, JE Duex, ... Communications Biology 3 (1), 720, 2020	138	2020
Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer ML Nickerson, GM Dancik, KM Im, MG Edwards, S Turan, J Brown, ... Clinical Cancer Research 20 (18), 4935-4948, 2014	132	2014
Transcriptomes of the B and T lineages compared by multiplatform microarray profiling MW Painter, S Davis, RR Hardy, D Mathis, C Benoist, Y Zhou, S Shinton, ... The Journal of Immunology 186 (5), 3047-3057, 2011	132	2011

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