|Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression|
LI Zhong, B Li, G Jayandharan, CS Mah, L Govindasamy, ...
Virology 381 (2), 194-202, 2008
|Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina|
H Petrs-Silva, A Dinculescu, Q Li, WT Deng, J Pang, SH Min, V Chiodo, ...
Molecular therapy 19 (2), 293-301, 2011
|Genetic diagnosis of haemophilia and other inherited bleeding disorders|
F Peyvandi, G Jayandharan, M Chandy, A Srivastava, SM Nakaya, ...
Haemophilia 12, 82-89, 2006
|High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines|
DM Markusic, RW Herzog, GV Aslanidi, BE Hoffman, B Li, M Li, ...
Molecular Therapy 18 (12), 2048-2056, 2010
|Innate immune responses to AAV vectors|
GL Rogers, AT Martino, GV Aslanidi, GR Jayandharan, A Srivastava, ...
Frontiers in microbiology 2, 194, 2011
|Basic biology of adeno-associated virus (AAV) vectors used in gene therapy|
B Balakrishnan, G R Jayandharan
Current gene therapy 14 (2), 86-100, 2014
|Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy|
GR Jayandharan, G Aslanidi, AT Martino, SC Jahn, GQ Perrin, ...
Proceedings of the National Academy of Sciences 108 (9), 3743-3748, 2011
|Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle|
C Qiao, W Zhang, Z Yuan, JH Shin, J Li, GR Jayandharan, L Zhong, ...
Human gene therapy 21 (10), 1343-1348, 2010
|Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3|
C Ling, Y Lu, JK Kalsi, GR Jayandharan, B Li, W Ma, B Cheng, SWY Gee, ...
Human gene therapy 21 (12), 1741-1747, 2010
|Adeno‐associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them|
S Hareendran, B Balakrishnan, D Sen, S Kumar, A Srivastava, ...
Reviews in medical virology 23 (6), 399-413, 2013
|Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of …|
G Jayandharan, RV Shaji, S Baidya, SC Nair, M Chandy, A Srivastava
Haemophilia 11 (5), 481-491, 2005
|Bioengineering of AAV2 Capsid at Specific Serine, Threonine, or Lysine Residues Improves Its Transduction Efficiency in Vitro and in Vivo|
N Gabriel, S Hareendran, D Sen, RA Gadkari, G Sudha, R Selot, ...
Human gene therapy methods 24 (2), 80-93, 2013
|The phenotypic heterogeneity of severe hemophilia|
GR Jayandharan, A Srivastava
Seminars in thrombosis and hemostasis 34 (01), 128-141, 2008
|High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy|
M Li, GR Jayandharan, B Li, C Ling, W Ma, A Srivastava, L Zhong
Human gene therapy 21 (11), 1527-1543, 2010
|Strategies for improving the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo|
GR Jayandharan, L Zhong, B Li, B Kachniarz, A Srivastava
Gene therapy 15 (18), 1287-1293, 2008
|Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo|
L Song, MA Kauss, E Kopin, M Chandra, T Ul-Hasan, E Miller, ...
Cytotherapy 15 (8), 986-998, 2013
|High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors|
GV Aslanidi, AE Rivers, L Ortiz, L Govindasamy, C Ling, GR Jayandharan, ...
Vaccine 30 (26), 3908-3917, 2012
|Nuclear factor (NF)‐κ B and its associated pathways are major molecular regulators of blood‐induced joint damage in a murine model of hemophilia|
D Sen, A Chapla, N Walter, V Daniel, A Srivastava, GR Jayandharan
Journal of Thrombosis and Haemostasis 11 (2), 293-306, 2013
|Informativeness of linkage analysis for genetic diagnosis of haemophilia A in India|
G Jayandharan, RV Shaji, B George, M Chandy, A Srivastava
Haemophilia 10 (5), 553-559, 2004
|Targeted Modifications in Adeno-Associated Virus Serotype 8 Capsid Improves Its Hepatic Gene Transfer Efficiency In Vivo|
D Sen, RA Gadkari, G Sudha, N Gabriel, YS Kumar, R Selot, R Samuel, ...
Human gene therapy methods 24 (2), 104-116, 2013