Tom Mikkelsen
Tom Mikkelsen
Ontario Brain Institute
Verified email at braininstitute.ca
TitleCited byYear
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network
Nature 455 (7216), 1061, 2008
48522008
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
Cell 155 (2), 462-477, 2013
24462013
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
PY Wen, DR Macdonald, DA Reardon, TF Cloughesy, AG Sorensen, ...
Journal of clinical oncology 28 (11), 1963-1972, 2010
24322010
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
J clin oncol 27 (28), 4733-4740, 2009
22082009
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
Cancer Genome Atlas Research Network
New England Journal of Medicine 372 (26), 2481-2498, 2015
12772015
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
11262012
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ...
Cell 164 (3), 550-563, 2016
8192016
Clonal expansion of p53 mutant cells is associated with brain tumour progression
D Sidransky, T Mikkelsen, K Schwechheimer, ML Rosenblum, ...
Nature 355 (6363), 846-847, 1992
7841992
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
L Sun, AM Hui, Q Su, A Vortmeyer, Y Kotliarov, S Pastorino, A Passaniti, ...
Cancer cell 9 (4), 287-300, 2006
6622006
Transforming fusions of FGFR and TACC genes in human glioblastoma
D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ...
Science 337 (6099), 1231-1235, 2012
5012012
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
4852018
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
DA Reardon, KL Fink, T Mikkelsen, TF Cloughesy, A O'Neill, S Plotkin, ...
Journal of clinical oncology 26 (34), 5610-5617, 2008
4852008
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
ME Linskey, DW Andrews, AL Asher, SH Burri, D Kondziolka, ...
Journal of neuro-oncology 96 (1), 45-68, 2010
4652010
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
4562018
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
NJ Szerlip, A Pedraza, D Chakravarty, M Azim, J McGuire, Y Fang, ...
Proceedings of the National Academy of Sciences 109 (8), 3041-3046, 2012
4202012
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant …
EA Chiocca, KM Abbed, S Tatter, DN Louis, FH Hochberg, F Barker, ...
Molecular Therapy 10 (5), 958-966, 2004
3942004
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
3632018
The integrated landscape of driver genomic alterations in glioblastoma
V Frattini, V Trifonov, JM Chan, A Castano, M Lia, F Abate, ST Keir, AX Ji, ...
Nature genetics 45 (10), 1141, 2013
3402013
Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma
TT Batchelor, P Mulholland, B Neyns, LB Nabors, M Campone, A Wick, ...
Journal of Clinical Oncology 31 (26), 3212, 2013
3392013
The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
SN Kalkanis, D Kondziolka, LE Gaspar, SH Burri, AL Asher, CS Cobbs, ...
Journal of neuro-oncology 96 (1), 33-43, 2010
3382010
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Articles 1–20