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Xander Wehrens, MD PhD
Xander Wehrens, MD PhD
Director, Cardiovascular Research Institute, Baylor College of Medicine
Verified email at bcm.edu - Homepage
Title
Cited by
Cited by
Year
FKBP12. 6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
XHT Wehrens, SE Lehnart, F Huang, JA Vest, SR Reiken, PJ Mohler, ...
Cell 113 (7), 829-840, 2003
9012003
Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
S Ather, W Chan, B Bozkurt, D Aguilar, K Ramasubbu, AA Zachariah, ...
Journal of the American College of Cardiology 59 (11), 998-1005, 2012
7982012
Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor
XHT Wehrens, SE Lehnart, SR Reiken, AR Marks
Circulation research 94 (6), e61-e70, 2004
7932004
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic …
N Voigt, N Li, Q Wang, W Wang, AW Trafford, I Abu-Taha, Q Sun, ...
Circulation 125 (17), 2059-2070, 2012
6532012
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
SE Lehnart, XHT Wehrens, S Reiken, S Warrier, AE Belevych, RD Harvey, ...
Cell 123 (1), 25-35, 2005
5912005
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
XHT Wehrens, SE Lehnart, SR Reiken, SX Deng, JA Vest, D Cervantes, ...
Science 304 (5668), 292-296, 2004
5812004
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation
N Voigt, J Heijman, Q Wang, DY Chiang, N Li, M Karck, XHT Wehrens, ...
Circulation 129 (2), 145-156, 2014
5002014
Calcium signaling and cardiac arrhythmias
AP Landstrom, D Dobrev, XHT Wehrens
Circulation research 120 (12), 1969-1993, 2017
4792017
Evidence for multiple mechanisms in human ventricular fibrillation
MP Nash, A Mourad, RH Clayton, PM Sutton, CP Bradley, M Hayward, ...
Circulation 114 (6), 536-542, 2006
473*2006
Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice
MG Chelu, S Sarma, S Sood, S Wang, RJ Van Oort, DG Skapura, N Li, ...
The Journal of clinical investigation 119 (7), 1940-1951, 2009
4642009
Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation
C Yao, T Veleva, L Scott Jr, S Cao, L Li, G Chen, P Jeyabal, X Pan, ...
Circulation 138 (20), 2227-2242, 2018
4342018
Intracellular calcium release and cardiac disease
XHT Wehrens, SE Lehnart, AR Marks
Annu. Rev. Physiol. 67, 69-98, 2005
4332005
Defective cardiac ryanodine receptor regulation during atrial fibrillation
JA Vest, XHT Wehrens, SR Reiken, SE Lehnart, D Dobrev, P Chandra, ...
Circulation 111 (16), 2025-2032, 2005
4302005
β-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
S Reiken, XHT Wehrens, JA Vest, A Barbone, S Klotz, D Mancini, ...
Circulation 107 (19), 2459-2466, 2003
4112003
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression
XHT Wehrens, SE Lehnart, S Reiken, JA Vest, A Wronska, AR Marks
Proceedings of the National Academy of Sciences 103 (3), 511-518, 2006
4092006
Circadian rhythms govern cardiac repolarization and arrhythmogenesis
D Jeyaraj, SM Haldar, X Wan, MD McCauley, JA Ripperger, K Hu, Y Lu, ...
Nature 483 (7387), 96-99, 2012
3942012
Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak
SE Lehnart, XHT Wehrens, PJ Laitinen, SR Reiken, SX Deng, Z Cheng, ...
Circulation 109 (25), 3208-3214, 2004
3792004
Transverse aortic constriction in mice
AC deAlmeida, RJ van Oort, XHT Wehrens
JoVE (Journal of Visualized Experiments), e1729, 2010
3562010
Evidence for multiple mechanisms in human ventricular fibrillation
MP Nash, A Mourad, RH Clayton, PM Sutton, CP Bradley, M Hayward, ...
Circulation 114 (6), 536-542, 2006
3432006
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure
RJ Van Oort, MD McCauley, SS Dixit, L Pereira, Y Yang, JL Respress, ...
Circulation 122 (25), 2669-2679, 2010
3362010
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