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Tyler Weaver
Tyler Weaver
Postdoctoral Fellow
Verificeret mail på kumc.edu
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Citeret af
Citeret af
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Reading more than histones: the prevalence of nucleic acid binding among reader domains
TM Weaver, EA Morrison, CA Musselman
Molecules 23 (10), 2614, 2018
622018
Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor
S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ...
ACS chemical biology 15 (1), 112-131, 2019
582019
Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association
KE Connelly, TM Weaver, A Alpsoy, BX Gu, CA Musselman, ...
Nucleic acids research 47 (5), 2289-2305, 2019
442019
Covalent modifications of histone H3K9 promote binding of CHD3
AH Tencer, KL Cox, L Di, JB Bridgers, J Lyu, X Wang, JK Sims, ...
Cell reports 21 (2), 455-466, 2017
442017
Rapid detection of urinary tract infections via bacterial nuclease activity
KS Flenker, EL Burghardt, N Dutta, WJ Burns, JM Grover, EJ Kenkel, ...
Molecular therapy 25 (6), 1353-1362, 2017
232017
The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail
TM Weaver, J Liu, KE Connelly, C Coble, K Varzavand, EC Dykhuizen, ...
Scientific Reports 9 (1), 987, 2019
222019
Structural basis for APE1 processing DNA damage in the nucleosome
TM Weaver, NM Hoitsma, JJ Spencer, L Gakhar, NJ Schnicker, ...
Nature Communications 13 (1), 5390, 2022
162022
Visualizing Rev1 catalyze protein-template DNA synthesis
TM Weaver, LM Cortez, TH Khoang, MT Washington, PK Agarwal, ...
Proceedings of the National Academy of Sciences 117 (41), 25494-25504, 2020
162020
Reprogramming CBX8-PRC1 function with a positive allosteric modulator
JL Suh, D Bsteh, B Hart, Y Si, TM Weaver, C Pribitzer, R Lau, S Soni, ...
Cell chemical biology 29 (4), 555-571. e11, 2022
152022
Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
TM Weaver, TH Click, TH Khoang, M Todd Washington, PK Agarwal, ...
Nature communications 13 (1), 2876, 2022
42022
New insights into DNA polymerase mechanisms provided by time-lapse crystallography
TM Weaver, MT Washington, BD Freudenthal
Current opinion in structural biology 77, 102465, 2022
22022
Generation of recombinant nucleosomes containing site-specific DNA damage
BJ Ryan, TM Weaver, JJ Spencer, BD Freudenthal
Base Excision Repair Pathway: Methods and Protocols, 55-76, 2023
12023
Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.
BL Schnable, MA Schaich, V Roginskaya, LP Leary, TM Weaver, ...
bioRxiv, 2023.10. 04.560925, 2023
12023
Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glycosylase 1
MA Schaich, TM Weaver, V Roginskaya, BD Freudenthal, B Van Houten
DNA repair 134, 103625, 2024
2024
Hierarchical determinants of the oxidation-induced mutational landscape in human cells.
C Cordero, KPM Mehta, TM Weaver, JA Ling, BD Freudenthal, D Cortez, ...
bioRxiv, 2024.04. 08.588428, 2024
2024
Regulation of the polycomb repressive complexes by histone reader domains
TM Weaver
University of Iowa, 2019
2019
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Artikler 1–16