Reading more than histones: the prevalence of nucleic acid binding among reader domains TM Weaver, EA Morrison, CA Musselman Molecules 23 (10), 2614, 2018 | 62 | 2018 |
Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ... ACS chemical biology 15 (1), 112-131, 2019 | 58 | 2019 |
Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association KE Connelly, TM Weaver, A Alpsoy, BX Gu, CA Musselman, ... Nucleic acids research 47 (5), 2289-2305, 2019 | 44 | 2019 |
Covalent modifications of histone H3K9 promote binding of CHD3 AH Tencer, KL Cox, L Di, JB Bridgers, J Lyu, X Wang, JK Sims, ... Cell reports 21 (2), 455-466, 2017 | 44 | 2017 |
Rapid detection of urinary tract infections via bacterial nuclease activity KS Flenker, EL Burghardt, N Dutta, WJ Burns, JM Grover, EJ Kenkel, ... Molecular therapy 25 (6), 1353-1362, 2017 | 23 | 2017 |
The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail TM Weaver, J Liu, KE Connelly, C Coble, K Varzavand, EC Dykhuizen, ... Scientific Reports 9 (1), 987, 2019 | 22 | 2019 |
Structural basis for APE1 processing DNA damage in the nucleosome TM Weaver, NM Hoitsma, JJ Spencer, L Gakhar, NJ Schnicker, ... Nature Communications 13 (1), 5390, 2022 | 16 | 2022 |
Visualizing Rev1 catalyze protein-template DNA synthesis TM Weaver, LM Cortez, TH Khoang, MT Washington, PK Agarwal, ... Proceedings of the National Academy of Sciences 117 (41), 25494-25504, 2020 | 16 | 2020 |
Reprogramming CBX8-PRC1 function with a positive allosteric modulator JL Suh, D Bsteh, B Hart, Y Si, TM Weaver, C Pribitzer, R Lau, S Soni, ... Cell chemical biology 29 (4), 555-571. e11, 2022 | 15 | 2022 |
Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1 TM Weaver, TH Click, TH Khoang, M Todd Washington, PK Agarwal, ... Nature communications 13 (1), 2876, 2022 | 4 | 2022 |
New insights into DNA polymerase mechanisms provided by time-lapse crystallography TM Weaver, MT Washington, BD Freudenthal Current opinion in structural biology 77, 102465, 2022 | 2 | 2022 |
Generation of recombinant nucleosomes containing site-specific DNA damage BJ Ryan, TM Weaver, JJ Spencer, BD Freudenthal Base Excision Repair Pathway: Methods and Protocols, 55-76, 2023 | 1 | 2023 |
Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine. BL Schnable, MA Schaich, V Roginskaya, LP Leary, TM Weaver, ... bioRxiv, 2023.10. 04.560925, 2023 | 1 | 2023 |
Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glycosylase 1 MA Schaich, TM Weaver, V Roginskaya, BD Freudenthal, B Van Houten DNA repair 134, 103625, 2024 | | 2024 |
Hierarchical determinants of the oxidation-induced mutational landscape in human cells. C Cordero, KPM Mehta, TM Weaver, JA Ling, BD Freudenthal, D Cortez, ... bioRxiv, 2024.04. 08.588428, 2024 | | 2024 |
Regulation of the polycomb repressive complexes by histone reader domains TM Weaver University of Iowa, 2019 | | 2019 |